Zeitschrift für Naturforschung / C / 38 (1983)

Zeitschrift Für Naturforschung

3'-Hydroxylation of 4'-methoxyisoflavones by Fusarium oxysporum f. lycopersici.

3'-Hydroxylation of isoflavones by Fusarium oxysporum f. lycopersici mainly proceeds with 4'-methoxy-7-hydroxyderivatives; this reaction is used for quantitative conversion of 14C-labelled isoflavones.

Photosensitized effects of furocoumarins: the possible role of singlet oxygen.

The capacity of various furocoumarins to generate singlet oxygen in aqueous solution has been determined. The antiproliferative and the skin-photosensitizing activities of the same furocoumarins did not show any correlation with the capacity to generate the singlet oxygen, while these photobiological properties could be correlated with the capacity of furocoumarins to induce photolesions to the...

Effect of 5'-terminated (2'-5')-oligoadenylates on cap degrading activities in rat liver nuclei.

(2'-5')-oligoadenylates bearing a 5'-terminal triphosphate or a 5'GTP-group inhibit the activity of a dinucleoside triphosphatase in rat liver nuclei thereby protecting mRNA against 5'-exonucleolytic degradation. (2'-5')-oligoadenylates, on the other hand, were known to enhance the activity of an endoribonuclease, RNaseF. Thus a synergistic effect may be assumed in vivo, i.e. cellular metabolis...

Circular permutation analysis of phage T4 DNA by electron microscopy.

Phage T4 is known to have a linear duplex chromosome that is circularly permuted and terminally repeated. We found, by denaturation and self-reannealing experiments, that circular permutation in T4 native DNA is not random. Their multimodal distribution of permutation is compatible with the "headful packaging" model with the additional specifications that the encapsulation of DNA starts at seve...